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Clarinex
CLARINEX® provides nondrowsy 24-hour relief from allergy symptoms caused by seasonal allergens such as ragweed, grass, and tree pollens and year-round allergens such as dust mite, animal dander, and mold spores.
Medications details | All details
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| Generic Clarinex 5 mg |
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Quantity |
Dosage |
Price |
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| Clarinex |
60 pills |
5mg |
$59.87 |
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| Clarinex |
90 pills |
5mg |
$80.24 |
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| Medication Prescription |
General Information
Clarinex, in an oral tablet formulation, was approved for the treatment of seasonal allergic rhinitis (SAR)in adults and children over 12 years of age in December 2001. In February 2002, Clarinex tablets were additionally approved for the treatment of perennial allergic rhinitis (PAR) and for symptomatic relief of chronic idiopathic urticaria (CIU) in adults and children over 12 years old. Clarinex is a once-daily non-sedating antihistamine that provides 24 hour relief.
An estimated 45 million Americans are affected by allergies. Allergic rhinitis (AR) is the most common allergic disorder in the United States, affecting up to 30% of the population.SAR is considered a response to outdoor allergens, while PAR pertains to indoor allergens. AR symptoms impact daily functioning at work, school and during leisure time, resulting in millions of absentee days each year.
Urticaria, known commonly as hives, affects an estimated 20% of Americans at some point in their lives. The condition results from a reaction to a substance, most commonly food, drugs or a topical agent. Urticaria is characterized by itchy, swollen welts on the skin.
Clinical Results
Approval of Clarinex for AR treatment is supported by four double-blind, placebo-controlled studies that enrolled over 2,300 SAR sufferersand two double-blind, placebo-controlled trials with over 1,000 subjects with PAR Results show that a single 5 mg dose of Clarinex provides 24 hours of relief from nasal and non-nasal SAR symptoms. During trials, Clarinex provided significantly greater relief than placebo.
Approval for CIU is based on two double-blind, placebo-controlled studies involving 416 subjects. Treatment with Clarinex significantly reduced the severity of pruritis when compared to placebo. Clarinex also performed superior to placebo at reducing the number and size of hives.
Side Effects
Adverse events associated with the use of Clarinex may include (but are not limited to) the following:
Pharyngitis
Dry mouth
Nausea
Dizziness
Somnolence
Fatigue
Myalgia
Mechanism of Action
Clarinex (desloratadine) is a long-acting tricyclic histamine antagonist with selective H-1 receptor histamine antagonist activity that offers clinically proven benefits for the management of AR and CIU. |
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